It's one of the great illustrator Norman Rockwell's series on Freedoms. I had a chance to see many of Rockwell's works a few years ago. His museum is not far from here in a beautiful region of the state called the Berkshires.
Rockwell painted all four freedoms that were outlined in a Franklin Delano Roosevelt address to Congress in 1941. Those are Freedom of Speech, Freedom of Religion, Freedom from Want, and Freedom from Fear.